INTERNACIONAL
Survivors still being found from Burma earthquake, but hopes begin to fade as deaths exceed 2,700
- A 7.7 magnitude earthquake rocked Burma on Friday, killing more than 2,700 people, compounding a humanitarian crisis caused by a civil war.
- The death toll is expected to rise, but the earthquake hit a wide swath of the country, leaving many areas without power, telephone or cell connections and damaging roads and bridges, leaving the full extent of the devastation hard to assess.
- The World Health Organization said more than 10,000 buildings are known to have collapsed or been severely damaged in Burma. The earthquake also hit neighboring Thailand, causing a high-rise building under construction to collapse and burying many workers.
Rescue workers saved a 63-year-old woman from the rubble of a building in Burma’s capital on Tuesday, but hope was fading of finding many more survivors of the violent earthquake that killed more than 2,700 people, compounding a humanitarian crisis caused by a civil war.
The fire department in Naypyitaw said the woman was successfully pulled from the rubble 91 hours after being buried when the building collapsed in the 7.7 magnitude earthquake that hit midday Friday. Experts say the likelihood of finding survivors drops dramatically after 72 hours.
Death toll numbers forecast to increase
The head of Burma’s military government, Senior Gen. Min Aung Hlaing, told a forum in Naypyitaw, that 2,719 people have now been found dead, with 4,521 others injured and 441 missing, Myanmar’s Western News online portal reported.
BURMA-THAILAND EARTHQUAKE: PATRICK SCHWARZENEGGER, ‘WHITE LOTUS’ CAST SEND PRAYERS AS DEATH TOLL PASSES 1,000
Those figures are widely expected to rise, but the earthquake hit a wide swath of the country, leaving many areas without power, telephone or cell connections and damaging roads and bridges, leaving the full extent of the devastation hard to assess.
Most of the reports so far have come from Mandalay, Burma’s second-largest city, which was near the epicenter of the earthquake, and Naypyitaw.
«The needs are massive, and they are rising by the hour,» said Julia Rees, UNICEF’s deputy representative for Burma.
Burma’s rescuers work through rubble of a collapsed building following Friday’s earthquake in Naypyitaw, Burma, on April 1, 2025. (AP Photo)
«The window for lifesaving response is closing. Across the affected areas, families are facing acute shortages of clean water, food, and medical supplies.»
Burma’s fire department said that 403 people have been rescued in Mandalay and 259 bodies have been found so far. In one incident alone, 50 Buddhist monks who were taking a religious exam in a monastery were killed when the building collapsed and 150 more are thought to be buried in the rubble.
Structural damage is extensive
The World Health Organization said that more than 10,000 buildings overall are known to have collapsed or been severely damaged in central and northwest Burma.
The earthquake also rocked neighboring Thailand, causing a high-rise building under construction to collapse and burying many workers.
Two bodies were pulled from the rubble on Monday and another was recovered Tuesday, but dozens were still missing. Overall, there were 21 people killed and 34 injured in Bangkok, primarily at the construction site.
In Burma, search and rescue efforts across the affected area paused briefly at midday on Tuesday as people stood for a minute in silent tribute to the dead.
MASSIVE 7.7 MAGNITUDE EARTHQUAKE ROCKS THAILAND, BURMA, COLLAPSING BUILDINGS AND KILLING MORE THAN 1,000
Relief efforts moving at a sluggish pace
Foreign aid workers have been arriving slowly to help in the rescue efforts, but progress was still slow with a lack of heavy machinery in many places.
In one site in Naypyitaw on Tuesday, workers formed a human chain, passing chunks of brick and concrete out hand-by-hand from the ruins of a collapsed building.
The Burma military government’s official Global New Light of Burma reported Tuesday that a team of Chinese rescuers saved four people the day before from the ruins of the Sky Villa, a large apartment complex that collapsed during the quake. They included a 5-year-old and a pregnant woman who had been trapped for more than 60 hours.
The same publication also reported two teenagers were able to crawl out of the rubble of the same building to where rescue crews were working, using their cellphone flashlights to help guide them. The rescue workers were then able to use details from what they told them to locate their grandmother and sibling.
International rescue teams from several countries are on the scene, including from Russia, China, India, the United Arab Emirates and several Southeast Asian countries. The U.S. Embassy said an American team had been sent but hadn’t yet arrived.
Aid pledges pouring in as officials warn of disease outbreak risk
Meantime, multiple countries have pledged millions in aid to assist Burma and humanitarian aid organizations with the monumental task ahead.
Even before the earthquake, more than 3 million people had been displaced from their homes by Burma’s brutal civil war, and nearly 20 million were in need, according to the U.N.
Many were already lacking in basic medical care and standard vaccinations, and the destruction of water and sanitation infrastructure by the earthquake raises the risk of disease outbreaks, warned the U.N.’s Office for the Coordination of Humanitarian Affairs.
«The displacement of thousands into overcrowded shelters, coupled with the destruction of water and sanitation infrastructure, has significantly heightened the risk of communicable disease outbreaks,» OCHA said in its latest report.
«Vulnerability to respiratory infections, skin diseases, vector-borne illnesses such as dengue fever, and vaccine-preventable diseases like measles is escalating,» it added.
The onset of monsoon season also a worry
Shelter is also a major problem, especially with the monsoon season looming.
Since the earthquake, many people have been sleeping outside, either because homes were destroyed or out of fear of aftershocks.
Civil war complicates disaster relief
Burma’s military seized power in 2021 from the democratically elected government of Aung San Suu Kyi, sparking what has turned into significant armed resistance and a brutal civil war.
Government forces have lost control of much of Burma, and many places were dangerous or impossible for aid groups to reach even before the quake.
Military attacks and those from some anti-military groups have not stopped in the aftermath of the earthquake, though the shadow opposition National Unity Government has called a unilateral ceasefire for its forces.
BURMESE GOVERNMENT DENIES CLAIMS IT KILLED 76 VILLAGERS
The NUG, established by elected lawmakers who were ousted in 2021, called for the international community to ensure humanitarian aid is delivered directly to the earthquake victims, urging «vigilance against any attempts by the military junta to divert or obstruct humanitarian assistance.»
«We are in a race against time to save lives,» the NUG said in a statement.
«Any obstruction to these efforts will have devastating consequences, not only due to the impact of the earthquake but also because of the junta’s continued brutality, which actively hinders the delivery of lifesaving assistance.»
It wasn’t immediately clear whether the military has been impeding humanitarian aid. In the past, it initially refused to allow in foreign rescue teams or many emergency supplies after Cyclone Nargis in 2008, which resulted in well more than 100,000 deaths. Even once it did allow foreign assistance, it was with severe restrictions.
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In this case, however, Min Aung Hlaing, pointedly said on the day of the earthquake that the country would accept outside help.
Tom Andrews, a monitor on rights in Burma commissioned by the U.N.-backed Human Rights Council, said on X that to facilitate aid, military attacks must stop.
«The focus in Burma must be on saving lives, not taking them,» he said.
INTERNACIONAL
Un medicamento para la diabetes podría ayudar a controlar el peso en hombres con cáncer de próstata
La metformina es un medicamento utilizado principalmente para tratar la diabetes tipo 2 que ayuda a controlar los niveles de glucosa en sangre.
Científicos de los Estados Unidos identificaron que se le podría dar otro uso al medicamento también. En hombres con cáncer de próstata, el fármaco podría producir un efecto similar al que genera el ejercicio intenso en el cuerpo.
Es porque la metformina eleva los niveles de una molécula clave para el equilibrio energético y el peso, aun cuando los pacientes no realizan actividad física.
El trabajo fue realizado por investigadores del Sylvester Comprehensive Cancer Center, en Miami, un centro especializado en cáncer. Lo publicaron en la revista científica EMBO Molecular Medicine.
Qué motivó a hacer el estudio
Muchos de los pacientes con cáncer de próstata sienten fatiga, dolores o presentan limitaciones físicas que hacen difícil mantener una rutina de ejercicios.
La terapia hormonal, utilizada para combatir el cáncer de próstata, puede alterar el metabolismo y provocar aumento de peso, resistencia a la insulina y riesgo cardiovascular.
Por eso, los científicos buscaron alternativas para ayudar a quienes no pueden moverse con facilidad durante el tratamiento.
El medicamento logró aumentar los niveles de N-lactoil-fenilalanina (Lac-Phe), una molécula que el cuerpo fabrica cuando necesita más energía.
Lac-Phe aparece cuando el lactato, que se produce al hacer esfuerzo, se une a la fenilalanina, un aminoácido que forma parte de las proteínas.
Estudios previos en animales y humanos ya habían relacionado altos niveles de Lac-Phe con menor apetito y mejor control del peso.
Señales del cuerpo, caminos de la medicina
Los investigadores observaron que la metformina elevó Lac-Phe en pacientes sin actividad física, y que los valores alcanzados eran parecidos a los que se ven luego de una sesión exigente de ejercicios.
Este dato llamó la atención porque muestra que ciertas rutas metabólicas pueden activarse incluso cuando no hay movimiento.
El estudio aclara que tomar metformina no reemplaza los beneficios del ejercicio físico, pero ayuda a entender cómo funcionan los mecanismos internos del metabolismo.
El objetivo es explorar si existen formas de proteger la salud metabólica en pacientes que no pueden hacer ejercicio debido a los tratamientos o a otros problemas.
La investigación también comprobó que los niveles de Lac-Phe elevados por la metformina no se vincularon con cambios en el antígeno prostático específico (PSA), el análisis de sangre que se usa para seguir la evolución del cáncer de próstata.
Esto significa que, aunque la molécula se relaciona con el metabolismo y el peso, no afecta directamente al tumor.
Metformina, una aliada inesperada
Además de Lac-Phe, la metformina elevó otra sustancia llamada GDF-15, aunque la relación de esta molécula con los cambios de peso fue menos clara.
El equipo dirigido por Marijo Bilusic, oncólogo y profesor en la Universidad de Miami, señaló que la combinación del trabajo de laboratorio y estudios clínicos permitió unir los resultados moleculares con datos de pacientes reales.
La doctora Priyamvada Rai, experta en biología tumoral, explicó que mantener la salud metabólica puede ser clave para que los pacientes toleren mejor los tratamientos y se sientan mejor en su vida diaria.
En tanto, el profesor David Lombard, del área de epigenética, agregó que estudiar el metabolismo celular ayuda a comprender el impacto de la metformina en personas con cáncer de próstata.
Los resultados se confirmaron en distintos contextos clínicos y también en pacientes tratados con otras terapias metabólicas.
Esto sugiere que Lac-Phe podría reflejar un ajuste más amplio del metabolismo, no solo un efecto exclusivo de la metformina.
La potencial utilidad de la metformina en pacientes con cáncer de próstata abre una nueva línea de investigación sobre cómo los medicamentos pueden apoyar el metabolismo cuando la actividad física no es posible o resulta muy difícil.
soledad,tercera edad,aislamiento,reflexión,vejez,salud mental,personas mayores,sociedad
INTERNACIONAL
‘Credible intelligence’ reveals North Korea’s successor to Kim Jong Un, South Korea says
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South Korea’s National Intelligence Service (NIS) thinks that North Korean leader Kim Jong Un’s daughter has been lined up to be her father’s eventual successor, lawmakers noted on Monday, according to Reuters.
The NIS indicated to lawmakers that its analysis stems from what it characterized as «credible intelligence» that it had gathered, Reuters reported, citing briefings by ruling and opposition party members following a closed-door parliamentary meeting.
Video footage posted last month showed Kim and his daughter on a tank.
KIM JONG UN APPEARS WITH TEENAGE DAUGHTER AT LIVE-FIRE ROCKET TEST IN NORTH KOREA
This photo provided by the North Korean government shows its leader Kim Jong Un, front right, his daughter, reportedly named Kim Ju Ae, and other soldiers on a tank at a military training base in North Korea, on March 19, 2026. (Korean Central News Agency/Korea News Service via AP, File)
The South Korean agency indicated that the scene of the girl driving a tank was meant to emphasize her supposed military aptitude and counter doubts concerning a female successor, lawmakers noted, according to the outlet.
North Korean state-run media KCNA published photos of the North Korean leader and his daughter with a tank last month, following prior images of the girl utilizing firearms, Reuters reported.
The daughter is thought to be about 13 years old and named Ju Ae.
IRAN’S WAR AGAINST THE US AND ISRAEL IS BEING FUELED BY NORTH KOREAN WEAPONS, EXPERT WARNS
In this photo provided by the North Korean government, its leader Kim Jong Un’s daughter, center, tries out a new pistol at a factory producing pistols and other light arms at an undisclosed place in North Korea Wednesday, March 11, 2026. (Korean Central News Agency/Korea News Service via AP)
The outlet reported that ruling Democratic Party lawmaker Park Sun-won indicated that the scenes are meant to pay «homage» to the North Korean leader’s military appearances years ago when he was being set up to succeed his father as regime leader.
Korea Institute for National Unification analyst Hong Min said the tank scene is not enough to determine that she has been established as her father’s successor, pointing out that she appeared with her father rather than independently, unlike her father’s independent military appearances as he was being groomed to take the helm.
NORTH KOREA TESTS SOLID-FUEL MISSILE ENGINE AS KIM BOOSTS THREAT TO US MAINLAND
This picture taken on December 20, 2025, and released by North Korea’s official Korean Central News Agency (KCNA) via KNS on Dec. 23, 2025, shows North Korean leader Kim Jong Un (R) and his daughter Ju Ae (L) inspecting the Milyong Hotel, which was recently completed in the Samjiyon tourist district of Ryanggang Province. (KCNA VIA KNS / AFP via Getty Images)
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North Korea is one of the world’s only nuclear-armed nations.
world, north korea, kim jong un
INTERNACIONAL
Newsom’s California rail project now expected to cost $126B, official admits, with still no tracks laid
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California’s delayed, over-budget high-speed train from Los Angeles to San Francisco is running fast in only one direction: Rising costs to even get rolling, which are now estimated to be $126 billion.
«Today, we estimate with the right optimization just over $125 billion,» California High Speed Rail Authority board member Anthony Williams told CBS’s «60 Minutes» on Sunday. «I think $126 billion is the current estimate for that.»
That is nearly four times the $33 billion price tag presented to voters in 2008, making the long-delayed project a black eye for Democratic-run California, derided as the latest political example of «waste» in deep-blue America and a «train to nowhere.»
«We’re now in 2026: There are no trains; there’s no track laid; it was a complete bait and switch,» Rep. Vince Fong, R-Calif., told «60 Minutes,» saying the project «needs to stop.»
NEWSOM TOUTS CALIFORNIA’S NUMEROUS LEGAL FIGHTS WITH TRUMP ADMINISTRATION IN FINAL STATE OF THE STATE
Construction continues on California’s high-speed rail project in Fresno County on March 24, 2025. (David Paul Morris/Bloomberg)
«The California high-speed rail nightmare is the probably quintessential example of government waste and mismanagement.»
California’s long-troubled high-speed rail project is facing renewed scrutiny after state Transportation Secretary Toks Omishakin acknowledged that many of its critics have a point.
«There were mistakes made,» Omishakin told CBS. «Some of the criticisms on this project, I think, are very fair.»
TRUMP ADMIN UNCOVERS ‘STAGGERING’ $8.6 BILLION IN SUSPECTED CALIFORNIA SMALL BUSINESS FRAUD
«I don’t think the voters fully understood, and neither did we in the public sector, what it was going to take to actually get this project delivered,» Omishakin added.
Taking aim at California Democratic Gov. Gavin Newsom, President Donald Trump called California’s project «the worst cost overrun, I’ve ever seen,» a statement he has in the past reserved for Federal Reserve Board Chair Jerome Powell’s Federal Reserve Building in Washington, D.C.
«This administration is working to usher in a Golden Age of Transportation,» Transportation Secretary Sean Duffy told CBS in a statement. «That vision includes high speed rail and we’re exploring opportunities to efficiently build that infrastructure in America.
NEWSOM’S FAILED LEADERSHIP HAS LET CALIFORNIA BECOME A LAND OF FRAUD AND SCAMS
«What this administration won’t stand for is boondoggle projects like Newsom’s Train to Nowhere that wasted billions in taxpayer dollars yet delivered nothing to the American people,» Duffy said. «Under President Trump, America is building again. We defunded Newsom’s disaster and created the first Trump Infrastructure Dividend. Those dollars will now actually fund critical projects that enhance safety on rail networks across America.»
Newsom himself cast doubt on the full San Francisco-to-Los Angeles plan in 2019, and the project now faces a funding gap of roughly $90 billion.
«For $10 billion, Elon Musk put 300 rockets in orbit; for $11 billion, the state of California has built 1,600 feet of elevated rail with no rail,» Palantir CTO Shyam Sankar said in 2024.
State officials say they remain confident more money can be found to dump into the project, but for now California’s high-speed rail stands as a costly symbol of ambition, delay and deep public skepticism.
‘THE DAILY SHOW’ ROASTS GAVIN NEWSOM ON HOMELESSNESS, HIGH-SPEED RAIL IN SATIRICAL ‘LEADING MAN’ VIDEO
«The ultimate 494 miles of building this out without the federal government’s help will be challenging: There’s no doubt about that,» Omishakin said.
Nearly two decades since the start of the project, no track has been laid, and the only major visible progress is on a Central Valley segment between Bakersfield and Merced, according to the report.
The project’s earliest projected opening is now 2033, far later than originally promised. Critics, including Bakersfield’s Fong, a member of the House Transportation Committee.
CALIFORNIA IS BROKE, BUT IT’S NOT TOO LATE FOR THE REST OF US
«The business plan that was put out in 2008 was very theoretical,» Fong said. «You know, ‘This is what we think is gonna happen.’
«And it became very clear that they didn’t have the specifics worked out.»
Fong has sought oversight and accountability on the waste, including 597 change orders that have cost more than $2.3 billion alone as of November 2025, which is nearly 7% of the initial $33 billion project estimate.
Gov. Gavin Newsom and California High-Speed Rail Authority CEO Ian Choudri, middle, greet Iron Workers Local 155 members at the Southern Railhead site in the Wasco/Shafter area in Wasco, Feb. 3, 2026. (Damian Dovarganes/AP)
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«Taxpayers deserve full transparency and accountability,» Fong wrote in a statement in February. «The high-speed rail nightmare is a glaring example of structural mismanagement.
«Reckless, repeated contract amendments have squandered resources and precious tax dollars. Hardworking California taxpayers cannot afford to let this continue. This project should be canceled before even more money and time are wasted.»
los angeles, costs, gavin newsom, san francisco, california
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