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As Iran weakens, questions grow over Mohammed bin Salman’s regional ambitions

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As Iran weakens, a power vacuum is emerging across the Middle East — and Saudi Arabia is moving to fill it by recalibrating relations with former rivals, hedging global partnerships and asserting a more independent foreign policy, according to several experts.
Javed Ali, former senior official at the National Security Council and professor at the University of Michigan, told Fox News Digital that «Since Iran’s 1979 revolution, both Saudi Arabia and Iran have vied for influence across the broader Muslim world. Mohammed bin Salman’s consolidation of power in the kingdom has also introduced a markedly different vision from that of his predecessors.»
Riyadh’s recent moves, from Yemen to Turkey, are fueling debate over whether Crown Prince Mohammed bin Salman’s expanding regional role still aligns with U.S. interests. As part of that recalibration, Bloomberg reported on Jan. 9 that Turkey is seeking entry into the Saudi–Pakistan mutual defense pact signed four months earlier, according to people familiar with the talks.
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Saudi Crown Prince Mohammed bin Salman chairs the inaugural session of the Shura Council in Riyadh, Saudi Arabia, September 10, 2025. (Saudi Press Agency/Handout via Reuters)
Michael Rubin, a senior fellow at the American Enterprise Institute, said Saudi Arabia’s current trajectory must be viewed through years of accumulated frustration with U.S. policy.
«To be fair to MBS, previous U.S. administrations did not uphold their end of the bargain either,» Rubin told Fox News Digital, pointing to repeated Houthi attacks on Saudi territory. «The Houthis launched hundreds of drones and rockets that the Obama administration ignored.»
Rubin said tensions deepened as Mohammed bin Salman pursued reforms long urged by U.S. policymakers, only to face sharp criticism from Washington. He cited the Biden administration’s decision to remove the Houthis’ terror designation.

President Donald Trump welcomes Saudi Arabia’s Crown Prince Mohammed bin Salman to the White House, Tuesday, Nov. 18, 2025, in Washington. (Mark Schiefelbein/AP)
«By no objective measure should Secretary of State Antony Blinken have removed the terror designation from the Houthis,» Rubin said, calling the move «pure spite directed at MBS and Donald Trump.»
Rubin said that decision marked a turning point. «MBS calculated that if the United States did not have his back, he would need to embrace a Plan B,» he said, describing outreach to Russia and China as tactical signaling rather than ideological realignment.
Saudi geopolitical researcher Salman Al-Ansari rejects claims that Riyadh is drifting ideologically or embracing Islamist movements, framing Saudi policy as interest-driven.

U.S. President Donald Trump poses for a family picture with Saudi Crown Prince and Prime Minister Mohammed bin Salman and other attendees during the U.S.-Saudi Investment Forum in Washington, D.C., U.S., Nov. 19, 2025. (Evelyn Hockstein/Reuters)
«Saudi Arabia does not base its foreign policy on ideological alignment, but on pragmatic considerations aimed at stability and development,» Al-Ansari told Fox News Digital. He said outreach to Turkey reflects an effort to de-escalate rivalries. «The rapprochement with Turkey reflects this diplomatic approach, which seeks to transform the Middle East from a region of chronic conflict into one of greater stability.»
Al-Ansari said the shift has already delivered results. «This shift has given Riyadh increased flexibility in engaging regional powers, a change Ankara quickly recognized and that has translated into expanding economic cooperation.»
He rejected claims of alignment with the Muslim Brotherhood. «Saudi Arabia designated the group as a terrorist organization in 2014, and this position remains unchanged,» he said.
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Crowds in southern Yemen are rallying for independence. Dec. 2025. (Ahmed Shehab)
Those competing interpretations of Saudi intent are now colliding most visibly in Yemen, where the Saudi-Emirati alliance originally formed to counter Iran’s Houthi proxy. While both entered the war to roll back Iranian influence, their strategies diverged. Riyadh backs a unified Yemeni state under the internationally recognized government, arguing fragmentation strengthens Iran. The UAE has supported southern separatists, including the Southern Transitional Council, prioritizing control over ports and security corridors.
In the last few days, Saudi and Yemeni government forces have largely recaptured southern and eastern Yemen from the UAE-backed Southern Transitional Council (STC), and the STC’s leader reportedly fled to the UAE amid the group’s reported dissolution, highlighting a sharp rift involving Emirati support for separatists
Rubin called Yemen the clearest warning sign. «This is best seen in Yemen, where he has been supporting the Muslim Brotherhood faction militarily and attacking the more secular Southern Forces in a way that only empowers al Qaeda in the Arabian Peninsula and the Houthis,» he said.
Al-Ansari countered that «differences with the UAE stem from its backing of separatist armed actors in Yemen, which complicates the political process, fragments the anti-Houthi front, and ultimately benefits the Iranian-backed Houthi militia.»
Rubin warned of long-term consequences. «By ‘blowback’ I mean the same Islamists MBS cultivates today will end up targeting Saudi Arabia in the future,» he said.
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People hold a banner with images of the President of the United Arab Emirates, Sheikh Mohamed bin Zayed Al Nahyan, and Crown Prince and Prime Minister Mohammed bin Salman of Saudi Arabia during a rally organised by Yemen’s main separatist group, the Southern Transitional Council (STC), in Aden, Yemen Dec. 21, 2025. (Fawaz Salman/Reuters)
With Iran weakened and regional power shifting, Washington now faces a central question: whether Saudi Arabia’s expanding role will reinforce U.S.-backed stability, or redefine the balance of power in ways that test the limits of the long-standing partnership.
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INTERNACIONAL
Descubren que el centro de la hipófisis, la glándula bajo el cerebro, sería la vía más segura para cirugías

Un grupo de científicos de México, Chile y Argentina descubrió una zona con pocos vasos sanguíneos en el centro de la glándula pituitaria de las personas. La hipófisis, también llamada glándula pituitaria, se encuentra en la base del cerebro y regula funciones hormonales esenciales.
“Nuestro trabajo aporta una región hipovascular en la hipófisis a la cual denominamos zona de entrada pituitaria. Abordar esta lesión quirúrgicamente para remover tumores en la región disminuye la probabilidad de sangrado y, por ende, las complicaciones postoperatorias”, resaltó en diálogo con Infobae Gerardo Marín, el primer autor del estudio.
Marín integra el Departamento de Neurocirugía del Hospital Regional 1° de Octubre, que depende del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado en México. El experto también forma parte de la Universidad Nacional Autónoma de México (UNAM).

Según el estudio que los investigadores publicaron en la revista World Neurosurgery, la región central de la hipófisis tiene menos vasos sanguíneos que sus bordes.
La investigación también fue realizada por expertos de la Universidad Nacional de Tucumán y la Universidad de Buenos Aires de la Argentina, y la Universidad de Valparaíso de Chile.
La glándula pituitaria controla el funcionamiento de otras glándulas del cuerpo. Se divide en dos partes: la adenohipófisis (lóbulo anterior) y la neurohipófisis (lóbulo posterior), que tienen funciones y estructuras distintas.

En medicina, la vascularización significa la cantidad y disposición de vasos sanguíneos en un tejido. Aunque la hipófisis recibe mucha sangre, las incisiones en su línea media suelen no alterar la función hormonal.
Los neurocirujanos habían notado que operaciones como las realizadas para la enfermedad de Cushing o hemi-hipofisectomías (extracción parcial de la hipófisis) suelen proteger la producción hormonal cuando se hacen por el centro.
Sospecharon que eso ocurría porque el centro de la hipófisis tenía menos vasos sanguíneos que los bordes.
Quisieron estudiar esa diferencia y entender si explicaba la “resiliencia” de la hipófisis tras cortes centrales.

El análisis se hizo en el Laboratorio de Neuroanatomía Microquirúrgica de la Universidad de Buenos Aires. Para el estudio, se usaron glándulas de tres adultos fallecidos sin enfermedades previas en esa zona.
Las muestras se prepararon con técnicas histológicas, que consisten en cortar el tejido en partes finísimas y teñirlas para ver sus detalles.
Para identificar los vasos sanguíneos se utilizó el marcador CD34, una proteína que aparece en las células de las paredes de los vasos. Así, se pudo contar cuántos vasos había en cada zona. Se hicieron cortes en dos planos: el plano sagital, que divide el cuerpo de adelante hacia atrás, y el plano coronal, que lo divide de lado a lado.
De esta forma, los investigadores compararon la cantidad de vasos en el centro y los bordes de la hipófisis.

Los resultados fueron contundentes: en el plano sagital, la densidad microvascular fue significativamente menor en la región de la línea media en comparación con la región periférica.
En el plano coronal, la diferencia no se observó. Los investigadores explicaron que eso se debe a que los vasos del centro están alineados de arriba hacia abajo, y el corte coronal los atraviesa, lo que hace que parezcan más numerosos.

La zona identificada es un corredor anatómico donde los vasos se alinean de forma vertical, lo que permite hacer cortes quirúrgicos más seguros por el centro.
El análisis detalló que la parte anterosuperior de la hipófisis tiene la mayor densidad de vasos, mientras que la posteroinferior tiene la menor.
“Esta información resulta clave para planificar operaciones sin poner en riesgo funciones hormonales”, aclaró Marín a Infobae.

“Necesitamos continuar diseccionando esta zona de entrada pituitaria con un mayor número de personas para saber qué tanto disminuyen los riesgos de las complicaciones neuroquirurgicas”, reconoció el doctor Marín en la entrevista con Infobae.
Además, “es fundamental confirmar que este hallazgo no sea exclusivo de pacientes con patología tumoral, sino que esté presente también en personas sin enfermedad hipofisaria, lo que garantizaría su aplicabilidad clínica general”, afirmó.
Aclaró que “los próximos estudios estarán dirigidos a revelar esas preguntas”.

Los investigadores sugirieron que los neurocirujanos tengan en cuenta la zona de entrada hipofisaria al planificar cirugías del centro de la glándula, sobre todo en operaciones para la enfermedad de Cushing y hemi-hipofisectomías.
“Si bien está limitado por un tamaño de muestra pequeño, estos resultados resaltan un aspecto previamente poco caracterizado de la angioarquitectura hipofisaria que puede representar un corredor más seguro para la intervención quirúrgica”, señalaron.

El equipo quiere ampliar el estudio con más muestras y sumar técnicas de imagen en pacientes vivos para confirmar la importancia clínica de la zona identificada.
Además, propusieron analizar otros aspectos, como la actividad metabólica de la hipófisis, para comprender mejor su funcionamiento.
El hallazgo de la zona hipovascular central en la glándula pituitaria redefine el mapa de la cirugía cerebral y abre nuevas rutas para proteger la función endocrina.
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Rand Paul says GOP colleagues ‘don’t give a s‑‑t about these people in the boats’: They ‘say they’re pro-life’

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Sen. Rand Paul, R-Ky., accused his «pro-life» Republican colleagues of not caring about the people killed in boat strikes near Venezuela who the Trump administration, without providing evidence, claims were trafficking fentanyl.
During an appearance on «The Joe Rogan Experience» released on Tuesday. Paul said GOP lawmakers «don’t give a s‑‑-» about the people who died on the vessels, blasting his colleagues for not granting the presumption of innocence.
«I look at my colleagues who say they’re pro-life, and they value God’s inspiration in life, but they don’t give a s‑‑- about these people in the boats,» Paul said. «Are they terrible people in the boats? I don’t know. They’re probably poor people in Venezuela and Colombia.»
«I guess what I don’t feel connected to my Republican colleagues is that those lives don’t matter at all, and we just blow them up. And against all justice, and against all laws of war, all laws of just war, we have never blown up people who were shipwrecked,» he added, referring to the administration’s reported targeting and killing of survivors of initial strikes who were clinging to wreckage.
RAND PAUL SAYS TRUMP’S THREAT TO BOMB IRAN ‘IS NOT THE ANSWER’: NOT THE ‘JOB OF THE AMERICAN GOVERNMENT’
Sen. Rand Paul accused his Republican colleagues of not caring about the people killed in boat strikes near Venezuela. (Getty Images)
The liberty-minded Republican said it is «against the military code of justice to do that.»
«We’re doing it and everybody just says, ‘Oh, well, they’re drug dealers,’» he said.
Paul criticized his fellow GOP lawmakers who have repeated the administration’s claims about the boats carrying fentanyl. He also took issue with colleagues who hold the position of, «Well, we’re at war with them. They’re committing war by bringing drugs into America.»
«They’re not even coming here,» Paul explained. «They’re going to these islands in the south part of the Caribbean. The cocaine — and it’s not fentanyl at all — the cocaine’s going to Europe.»
He emphasized that «those little boats can’t get here.»
«No one’s even asked this common question: Those boats have these four engines on them. They’re outboard boats. You can probably go about 100 miles before you have to refuel. Two thousand miles from us, they’d have to refuel 20 times to get here,» Paul said.

Sen. Rand Paul said GOP lawmakers «don’t give a s‑‑t» about the people who died on the vessels. (Tom Williams/CQ-Roll Call, Inc )
The senator accused the administration of conducting the boat strikes to create «a pretense and a false argument» ahead of the operation to attack Venezuela and arrest its president, Nicolás Maduro.
«It’s all been a pretense for arresting Maduro,» he said. «So, we have to set up the predicate. We got to show you we care about drugs.»
Paul helped the Senate advance a resolution last week that would limit Trump’s ability to conduct further attacks against Venezuela after the U.S. military’s recent move to strike the country and capture Maduro, which the Kentucky Republican said amounts to war. The Upper Chamber could pass the measure later this week, although it faces an uphill battle in the House despite some support from Republicans.
«I think bombing a capital and removing the head of state is, by all definitions, war,» Paul told reporters before the procedural vote last week. «Does this mean we have carte blanche that the president can make the decision any time, anywhere, to invade a foreign country and remove people that we’ve accused of a crime?»
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Sen. Rand Paul accused the Trump administration of conducting the boat strikes to create «a pretense and a false argument» ahead of the move to attack Venezuela and arrest its president. (ANDREW CABALLERO-REYNOLDS / AFP via Getty Images)
The lawmaker has repeatedly criticized the administration’s boat strikes on alleged narco-terrorists in recent months, often raising concerns about killing people without due process and the possibility of killing innocent people. The senator previously cited Coast Guard statistics that show a significant percentage of boats boarded on suspicion of drug trafficking are innocent.
Paul said on «The Joe Rogan Experience» that he believes the administration might attack Mexico next, which Trump has signaled could be a future target.
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«They want to do that next. They want to bomb Mexico,» Paul said.
Trump has said cartels are «running Mexico» and that «something’s going to have to be done» because Mexican President Claudia Sheinbaum is «very frightened» of the cartels.
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Passengers baffled and confused after screams burst from beneath taxiing Air Canada plane

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Passengers aboard a taxiing aircraft were reportedly left horrified last month when chilling screams suddenly echoed from beneath the cabin just moments before takeoff.
According to the officials, a ground crew member became trapped inside the plane’s cargo hold when doors «inadvertently closed» behind him, according to local station CBC.
The incident happened on Dec. 13 when Air Canada Flight 1502 was preparing to depart Toronto Pearson Airport for Moncton, New Brunswick, the outlet said.
The Airbus flight, which was carrying 184 passengers, was ultimately canceled following the incident.
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An Air Canada plane is seen at Pearson International Airport in Toronto, Canada, on Aug. 14, 2025. (Arrush Chopra/NurPhoto via Getty Images)
Passengers told CBC that distressing sounds of muffled banging and desperate screams quickly filled the rear of the aircraft as it began taxiing toward the runway, prompting flight attendants to sprint down the aisle in alarm.
«Some of the people that were sitting towards the back of the plane heard the person screaming and banging, trying to get their attention,» passenger Gabrielle Caron said.
«We could see the crew gathering around the plane, so we knew something was happening,» she added. «Then, the pilot tells us that there is someone from the crew in the luggage hold.»
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An employee loads suitcases onto an aircraft. (Christophe Gateau/picture alliance via Getty Images)
The aircraft reportedly halted before reaching the runway. Moments later, the trapped ground crew member emerged safely from the cargo and entered the cabin, reassuring shaken passengers that he was unharmed, Caron reported.
Air Canada confirmed to CBC that no injuries were reported in the incident.
Caron added that the crew member involved was reportedly assisting ground staff by loading items as an extra set of hands and may have been left unaccounted for when the doors closed.

Air Canada flights are stationed outside Toronto Pearson Airport. (Nick Lachance/Toronto Star via Getty Images)
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The plane eventually returned to the terminal, where passengers were asked to disembark while the flight crew completed necessary paperwork, CBC reported.
The flight was ultimately canceled after several delays, the outlet said.
Fox News Digital reached out to Air Canada for more information.
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